SWISS POPULATION-DATA ON THE LOCI HLA-DQ-ALPHA, LDLR, GYPA, HBGG, D7S8, GC AND D1S80

被引:28
|
作者
HOCHMEISTER, MN [1 ]
BUDOWLE, B [1 ]
BORER, UV [1 ]
DIRNHOFER, R [1 ]
机构
[1] FED BUR INVEST ACAD,CTR FORENS SCI RES & TRAINING,QUANTICO,VA 22135
关键词
SWISS; POPULATION DATABASES; PCR; HARDY-WEINBERG EXPECTATIONS; HLA-DQ-ALPHA; LDLR; GYPA; HBGG; D7S8; GC; D1S80;
D O I
10.1016/0379-0738(94)90088-4
中图分类号
DF [法律]; D9 [法律]; R [医药、卫生];
学科分类号
0301 ; 10 ;
摘要
Allele and genotype frequencies for seven polymerase chain reaction-based DNA genetic markers were determined in a Swiss sample population. The loci are D1S80, HLA-DQ alpha, low density lipoprotein receptor, glycophorin A, hemoglobin G gammaglobin, D7S8, and group-specific component. All loci meet Hardy-Weinberg expectations. In addition, there is no detectable association of alleles between loci. The frequency data can be used in forensic analyses and paternity tests to estimate the frequency of a DNA profile in the Swiss population.
引用
收藏
页码:175 / 184
页数:10
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