LIPID A MUTANTS OF VIBRIO-CHOLERAE - ISOLATION AND PARTIAL CHARACTERIZATION

被引：5
|
作者：
PAUL, S
SEN, AK
BANERJEE, N
CHATTERJEE, AN
DAS, J
机构：
[1] INDIAN INST CHEM BIOL,DIV BIOPHYS,CALCUTTA 700032,W BENGAL,INDIA
[2] INDIAN INST CHEM BIOL,DEPT ORGAN CHEM,CALCUTTA 700032,W BENGAL,INDIA
[3] JADAVPUR UNIV,DEPT FOOD TECH & BIOCHEM ENGN,CALCUTTA 700032,W BENGAL,INDIA
来源：
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1990年 / 169卷 / 01期
关键词：
D O I：
10.1016/0006-291X(90)91441-T
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Vibriocholerae mutants resistant to common antibiotics and neutral and anionic detergents were isolated. Analysis of isolated outer membranes revealed a significant deficiency in the acylation of lipid A in the resistant strains. The content of amide-linked and ester-bound fatty acids in the lipid A of the mutant strains compared to that of the wild type was about 50-56% and 29-37% respectively. This defect was specific for lipid A as there was no change in the acylation of phospholipids. The reduction in fatty acid content of lipid A was reflected in the altered endotoxic properties in the mutant strains. © 1990.
引用
收藏
页码：116 / 122
页数：7
相关论文
共 50 条
  • [21] OBTAINING VIBRIO-CHOLERAE MUTANTS WITH ALTERED TOXIN PRODUCTION
    LIVANOVA, LF
    EROSHENKO, GA
    SMIRNOVA, NI
    ZHURNAL MIKROBIOLOGII EPIDEMIOLOGII I IMMUNOBIOLOGII, 1985, (02): : 38 - &
  • [22] LYSOGENY OF VIBRIO-CHOLERAE AND VIBRIO-CHOLERAE EL-TOR
    TOMOV, A
    CVETKOVAGEORGIEVA, E
    FOLIA MICROBIOLOGICA, 1976, 21 (04) : 321 - 321
  • [23] ISOLATION AND CHARACTERIZATION OF THE VIBRIO-CHOLERAE ACFA GENE, REQUIRED FOR EFFICIENT INTESTINAL COLONIZATION
    HUGHES, KJ
    EVERISS, KD
    KOVACH, ME
    PETERSON, KM
    GENE, 1995, 156 (01) : 59 - 61
  • [24] PRODUCTION AND PARTIAL CHARACTERIZATION OF PILI ON NON-O1 VIBRIO-CHOLERAE
    HONDA, T
    KASEMSUKSAKUL, K
    OGUCHI, T
    KOHDA, M
    MIWATANI, T
    JOURNAL OF INFECTIOUS DISEASES, 1988, 157 (01): : 217 - 218
  • [25] CHARACTERIZATION OF VIBRIO-CHOLERAE ISOLATED FROM OYSTERS
    TWEDT, RM
    MADDEN, JM
    HUNT, JM
    FRANCIS, DW
    PEELER, JT
    DURAN, AP
    HEBERT, WO
    MCCAY, SG
    RODERICK, CN
    SPITE, GT
    WAZENSKI, TJ
    APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 1981, 41 (06) : 1475 - 1478
  • [26] EVALUATION OF MEDIA FOR THE ISOLATION OF VIBRIO-CHOLERAE FROM FOOD
    BUSHELL, R
    FOOD TECHNOLOGY IN AUSTRALIA, 1984, 36 (05): : 223 - 226
  • [27] IMMUNOLOGIC CHARACTERIZATION OF A MUCINOLYTIC ENZYME OF VIBRIO-CHOLERAE
    JENSEN, KE
    JOURNAL OF INFECTIOUS DISEASES, 1953, 93 (01): : 107 - 110
  • [28] CHARACTERIZATION OF A FLAGELLAR SHEATH PROTEIN OF VIBRIO-CHOLERAE
    HRANITZKY, KW
    MULHOLLAND, A
    LARSON, AD
    EUBANKS, ER
    HART, LT
    INFECTION AND IMMUNITY, 1980, 27 (02) : 597 - 603
  • [29] CHARACTERIZATION OF SURFACE-PROPERTIES OF VIBRIO-CHOLERAE
    KABIR, S
    ALI, S
    INFECTION AND IMMUNITY, 1983, 39 (03) : 1048 - 1058
  • [30] LIPOPOLYSACCHARIDES OF R-MUTANTS ISOLATED FROM VIBRIO-CHOLERAE
    HISATSUNE, K
    KONDO, S
    BIOCHEMICAL JOURNAL, 1980, 185 (01) : 77 - 81
12345