STIMULATION OF GROWTH OF CANDIDA-GUILLIERMONDII AND STREPTOCOCCUS-FAECALIS BY SEROTONIN

Periodic addition of serotonin to the culture medium during growth of the yeast Candida guilliermondii and the bacterium Streptoccus faecalis has a stimulating effect on growth of these cultures. The effect is manifested as activation of cell multiplication in the lag phase, accelerated passage of the cultures through the logarithmic phase of growth, and the more rapid reaching of the stationary phase. Addition of serotonin at intervals of 2 h to the growth medium in a concentration of 10(-7) M provided optimal conditions for realization of its stimulating action.