In-situ TEM observation of rock salt crystal precipitation in liposome

被引：0

作者：

Ai, Haruka ^{[1
]}

Moriya, Naoto ^{[1
]}

Ube, Takuji ^{[1
]}

Hananoto, Takashi ^{[2
]}

Arai, Yoshihiro ^{[3
]}

Murata, Kazusyoshi ^{[4
]}

Ishiguro, Takashi ^{[1
]}

机构：

[1] Tokyo Univ Sci, Dept Mat Sci & Technol, Katsushika Ku, 6-3-1 Niijyuku, Tokyo 1258585, Japan

[2] Tokyo Inst Technol, Dept Met & Ceram Sci, Meguro Ku, 2-12-1-S8-6 Ookayama, Tokyo 1528550, Japan

[3] Terabase Inc, 3-5-1-102 Hanenishi, Okazaki, Aichi 4440838, Japan

[4] Natl Inst Physiol Sci, 38 Nishigonaka, Okazaki, Aichi 4448585, Japan

来源：

MRS ADVANCES | 2016年 / 1卷 / 25期

基金：

日本学术振兴会;

关键词：

D O I：

10.1557/adv.2016.277

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

Liposome reinforced by adding cholesterol Was Synthesized using the dipalmitoyl-phosphatidylcholine (DPPC). Phase stability of the phospholipid bilayers Was examined by FTIR spectroscopy. The reinforced liposomcs filled with ultrapurc water or physiological saline were observed by the conventional TEM equipped with a mass spectrometer. It was confirmed that the liposomcs filled with water or saline solution were stable in the vacuum at room temperature. However, during electron irradiation, water molecules escaped gradually, and a single crystal of rock salt precipitated in the liposome.

引用

页码：1871 / 1876

页数：6

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