Two cases of Langerhans' cell histiocytosis of the frontal bone are presented. This condition was previously known as eosinophilic granuloma and rarely involves the orbit but may be associated with widespread and life-threatening disease. Clinical, radiological and histopathological features are presented. A discussion of the light and electron microscopic appearances, investigation and management follows.
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All India Inst Med Sci, Dept Pediat, Div Pediat Oncol, New Delhi 110029, IndiaAll India Inst Med Sci, Dept Pediat, Div Pediat Oncol, New Delhi 110029, India
Seth, R.
Thavaraj, Vasantha
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All India Inst Med Sci, Dept Pediat, Div Pediat Oncol, New Delhi 110029, IndiaAll India Inst Med Sci, Dept Pediat, Div Pediat Oncol, New Delhi 110029, India
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Univ Paris 05, CHU Ambroise Pare, Serv Med Interne, F-92104 Boulogne, FranceUniv Paris 05, CHU Ambroise Pare, Serv Med Interne, F-92104 Boulogne, France
Hiar, I
Melander, C
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Univ Paris 05, CHU Ambroise Pare, Serv Med Interne, F-92104 Boulogne, FranceUniv Paris 05, CHU Ambroise Pare, Serv Med Interne, F-92104 Boulogne, France
Melander, C
de Lemtdes, CR
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Univ Paris 05, CHU Ambroise Pare, Serv Med Interne, F-92104 Boulogne, FranceUniv Paris 05, CHU Ambroise Pare, Serv Med Interne, F-92104 Boulogne, France
de Lemtdes, CR
Hanslik, T
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Univ Paris 05, CHU Ambroise Pare, Serv Med Interne, F-92104 Boulogne, FranceUniv Paris 05, CHU Ambroise Pare, Serv Med Interne, F-92104 Boulogne, France
Hanslik, T
Princeau, J
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Univ Paris 05, CHU Ambroise Pare, Serv Med Interne, F-92104 Boulogne, FranceUniv Paris 05, CHU Ambroise Pare, Serv Med Interne, F-92104 Boulogne, France
Princeau, J
Bafounta, ML
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Univ Paris 05, CHU Ambroise Pare, Serv Med Interne, F-92104 Boulogne, FranceUniv Paris 05, CHU Ambroise Pare, Serv Med Interne, F-92104 Boulogne, France
Bafounta, ML
Baglin, A
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Univ Paris 05, CHU Ambroise Pare, Serv Med Interne, F-92104 Boulogne, FranceUniv Paris 05, CHU Ambroise Pare, Serv Med Interne, F-92104 Boulogne, France