INDUCTION OF SYNAPTIC EXTRACELLULAR-MATRIX MOLECULES AT ECTOPIC NEUROMUSCULAR-JUNCTIONS

被引：3
|
作者：
KO, CP
FOLSOM, DB
机构：
[1] Department of Biological Sciences, University of Southern California, Los Angeles
来源：
DEVELOPMENTAL BRAIN RESEARCH | 1990年 / 53卷 / 01期
关键词：
Ectopic neuromuscular junction; Extracellular matrix; Peanut agglutinin; Synaptogenesis;
D O I：
10.1016/0165-3806(90)90131-H
中图分类号：
Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
The induction of synapse-specific molecules recognized by peanut agglutinin (PNA) was examined at ectopic neuromuscular junctions in adult frog muscles using light and electron microscopy. In normal frog muscles, PNA specifically recognizes the extracellular matrix at neuromuscular junctions but not at extrajunctional regions. This report shows binding of PNA at ectopic neuromuscular junctions which were initially extrasynaptic and hence unrecognized by PNA. Results suggest that synapse-specific extracellular matrix molecules can be induced de novo at new junctional sites. © 1990.
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页码：121 / 124
页数：4
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