PROTECTIVE AND ANTIBODY-RESPONSE TO A SYNTHETIC PEPTIDE FOOT-AND-MOUTH-DISEASE VACCINE IN CATTLE

被引：0
|
作者：
VENKATARAMANAN, R
RAI, DV
PATTNAIK, B
MUKHOPADHYAY, AK
机构：
来源：
INDIAN JOURNAL OF ANIMAL SCIENCES | 1994年 / 64卷 / 01期
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中图分类号：
S8 [畜牧、 动物医学、狩猎、蚕、蜂];
学科分类号：
0905 ;
摘要：
A synthetic peptide representing the region 136-151 of VP1 protein of A(22) foot-and-mouth disease virus was used in cattle, and immune response was analysed. High levels of neutralizing antibody were induced which showed peak titer 30th day post-vaccination, The vaccinated cattle were completely protected against virulent challenge. The peptide vaccine was as efficaceous as the whole-virus-gel vaccine in terms of neutralizing antibody and protection. Incorporation of glutamine muramyl dipeptide (GMDP) in peptide preparation did not enhance antibody activity.
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页码：9 / 13
页数：5
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