SMALL ROUND STRUCTURED VIRUS ASSOCIATED WITH AN OUTBREAK OF ACUTE GASTROENTERITIS IN CHIBA, JAPAN

被引:9
|
作者
KASUGA, K [1 ]
TOKIEDA, M [1 ]
OHTAWARA, M [1 ]
UTAGAWA, E [1 ]
YAMAZAKI, S [1 ]
机构
[1] NATL INST HLTH,CENT VIRUS DIAGNOST LAB,MUSASHI MURAYAMA,TOKYO 19012,JAPAN
来源
JAPANESE JOURNAL OF MEDICAL SCIENCE & BIOLOGY | 1990年 / 43卷 / 04期
关键词
D O I
10.7883/yoken1952.43.111
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
In an outbreak of acute gastroenteritis which originated in a restaurant in Chiba, Japan, in December, 1987, small round structured virus (SRSV) particles were observed by electron microscopy in 14 of 16 stool specimens from patients. The particles were 30 to 35 nm in diameter, possessed amorphous surface structure surrounded by fine projections and had a buoyant density of 1.36 to 1.37 g/ml in cesium chloride. Serological responses to the SRSV were found by immune electron microscopy and Western blot (WB) assay in paired sera of 12 of 19 patients. Furthermore, WB analysis revealed that the antibody against SRSV was cross-reactive to other SRSV, Tokyo 86/510. © 1990, National Institute of Infectious Diseases, Japanese Journal of Infectious Diseases Editorial Committee. All rights reserved.
引用
收藏
页码:111 / 121
页数:11
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