Histopathological Spectrum of Central Nervous System Tumors: A Single Centre Study of 100 Cases

Introduction: Central nervous system (CNS) tumors are not frequent tumors with primary malignant brain tumors accounting for 2% of all cancers in the U.S adults. The incidence rates are lower in developing countries like compared to the developed countries while increased rates have been observed in both. Purpose: The aim of the present study is to study the histopathological spectrum of CNS tumors irrespective of age in single tertiary care center. Material and Methods: The present 5 years study from a single tertiary care center, patient clinically diagnosed with CNS tumors and registered between 2009 and 2014 in pathology department were included and classifi ed according to WHO 2007 classifi cation along with grading of the tumor. Results: A wide range of histopathological spectrum of CNS tumors was observed and was classifi ed according to the recent WHO classifi cation system. The primary CNS tumors were graded from Grade 1 to Grade 1V. Overall tumors of neuroepithelial tissue (51.7%) was the most common entity followed by the tumors of meninges (34.8%), metastatic tumors (5.6%), tumors of peripheral nerves (4.5%), tumors of the sellar region (2.3%), and lymphomas and hematopoietic neoplasm (1.1%). Conclusion: Rising global trends in the incidence of CNS tumors, irrespective of age have been observed. The present study highlights the histological diversity in CNS tumors in both, adult as well as pediatric age groups.