STUDIES ON STILBENES IN RED WINE

Stilbenes are non-flavonoid phenolic compounds that are synthesized in the form of monomers and oligomers of numerous plant species, including the Vitaceae family. The interest of researchers in stilbenes is due to their many biological activities, including the prevention and treatment of various chronic diseases associated with aging. More than 100 stilbenes have been identified in black grapes and red wine; of these, E-resveratrol is the most interesting compound due to its biological activities in vitro and in vivo. The effect of resveratrol on health (protection against cardiovascular disease, neurodegenerative diseases, cancer prevention, cellular aging, antioxidant effect, anti-tumor protection, etc.) was highlighted in the early 1990s, when a connection between red wine consumption and positive effects of resveratrol in the human body.