Cladribine is the first disease modifying treatment (DMT) for relapsing remitting multiple sclerosis (RRMS) that progressed straight to a positive final recommendation in the NICE appraisal process. The final recommendations were published in December 2017.(1) An agreement between NHS England and Merck, the manufacturer of cladribine (Mavenclad), will allow MS patients who are suffering from highly active or rapidly evolving RRMS to access the drug. Here, the authors discuss the clinical and economic considerations for cladribine usage.
机构:
Tampere Univ, Fac Med & Hlth Technol, Tampere, Finland
Tampere Univ Hosp, Dept Neurol, Tampere, FinlandTampere Univ, Fac Med & Hlth Technol, Tampere, Finland
Rauma, Ilkka
Viitala, Matias
论文数: 0引用数: 0
h-index: 0
机构:
StellarQ Ltd, Turku, FinlandTampere Univ, Fac Med & Hlth Technol, Tampere, Finland
Viitala, Matias
Kuusisto, Hanna
论文数: 0引用数: 0
h-index: 0
机构:
Tampere Univ Hosp, Dept Neurol, Tampere, Finland
Univ Eastern Finland, Dept Hlth & Social Management, Kuopio, FinlandTampere Univ, Fac Med & Hlth Technol, Tampere, Finland
Kuusisto, Hanna
Atula, Sari
论文数: 0引用数: 0
h-index: 0
机构:
Helsinki Univ Hosp, Neuroctr, Helsinki, Finland
Univ Helsinki, Dept Neurosci, Helsinki, FinlandTampere Univ, Fac Med & Hlth Technol, Tampere, Finland
Atula, Sari
Sipila, Jussi O. T.
论文数: 0引用数: 0
h-index: 0
机构:
North Karelia Cent Hosp, Siun Sote, Dept Neurol, Joensuu, Finland
Univ Turku, Clin Neurosci, Turku, FinlandTampere Univ, Fac Med & Hlth Technol, Tampere, Finland
Sipila, Jussi O. T.
Ryytty, Mervi
论文数: 0引用数: 0
h-index: 0
机构:
Univ Oulu, Res Unit Clin Neurosci, Neurol, Oulu, Finland
Oulu Univ Hosp, Med Res Ctr, Oulu, FinlandTampere Univ, Fac Med & Hlth Technol, Tampere, Finland
Ryytty, Mervi
Soilu-Hanninen, Merja
论文数: 0引用数: 0
h-index: 0
机构:
Univ Turku, Clin Neurosci, Turku, Finland
Turku Univ Hosp, Neuroctr, Turku, FinlandTampere Univ, Fac Med & Hlth Technol, Tampere, Finland
Soilu-Hanninen, Merja
Jarvinen, Elina
论文数: 0引用数: 0
h-index: 0
机构:
Merck Oy, Espoo, FinlandTampere Univ, Fac Med & Hlth Technol, Tampere, Finland
机构:
Clermont Ferrand Univ Hosp, Dept Neurol, 58 Rue Montalembert, F-63003 Clermont Ferrand 1, FranceClermont Ferrand Univ Hosp, Dept Neurol, 58 Rue Montalembert, F-63003 Clermont Ferrand 1, France
Clavelou, Pierre
Castelnovo, Giovanni
论文数: 0引用数: 0
h-index: 0
机构:
Nimes Univ Hosp, Hop Caremeau, Dept Neurol, Nimes, FranceClermont Ferrand Univ Hosp, Dept Neurol, 58 Rue Montalembert, F-63003 Clermont Ferrand 1, France
Castelnovo, Giovanni
Pourcher, Valerie
论文数: 0引用数: 0
h-index: 0
机构:
Sorbonne Univ, Pitie Salpetriere Hosp, AP HP, Dept Infect & Trop Dis,INSERM 1136,Inst Pierre Lo, Paris, FranceClermont Ferrand Univ Hosp, Dept Neurol, 58 Rue Montalembert, F-63003 Clermont Ferrand 1, France
Pourcher, Valerie
论文数: 引用数:
h-index:
机构:
De Seze, Jerome
论文数: 引用数:
h-index:
机构:
Vermersch, Patrick
Ben-Amor, Ali-Frederic
论文数: 0引用数: 0
h-index: 0
机构:
Ares Trading SA, Global Med Affairs Neurol & Immunol, Eysins, SwitzerlandClermont Ferrand Univ Hosp, Dept Neurol, 58 Rue Montalembert, F-63003 Clermont Ferrand 1, France
Ben-Amor, Ali-Frederic
Savarin, Carine
论文数: 0引用数: 0
h-index: 0
机构:
Merck Sante, Med Affairs, Neurol Dept, Lyon, FranceClermont Ferrand Univ Hosp, Dept Neurol, 58 Rue Montalembert, F-63003 Clermont Ferrand 1, France
机构:
Royal London Hosp, Barts Hlth NHS Trust, London, EnglandQueen Mary Univ London, Barts & London Sch Med & Dent, Blizard Inst, 4 Newark St, London E1 2AT, England
机构:
Rutgers State Univ, New Jersey Med Sch, Newark, NJ USARutgers State Univ, New Jersey Med Sch, Newark, NJ USA
Cook, S.
Leist, T.
论文数: 0引用数: 0
h-index: 0
机构:
Thomas Jefferson Univ, Jefferson Med Coll, Div Clin Neuroimmunol, Philadelphia, PA 19107 USARutgers State Univ, New Jersey Med Sch, Newark, NJ USA
Leist, T.
Comi, G.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Vita Salute San Raffaele, Osped San Raffaele, Dept Neurol, Milan, Italy
Univ Vita Salute San Raffaele, Osped San Raffaele, Inst Expt Neurol, Milan, ItalyRutgers State Univ, New Jersey Med Sch, Newark, NJ USA
Comi, G.
Montalban, X.
论文数: 0引用数: 0
h-index: 0
机构:
Hosp Univ Vall dHebron, Dept Neurol Neuroimmunol, Barcelona, SpainRutgers State Univ, New Jersey Med Sch, Newark, NJ USA
Montalban, X.
Sylvester, E.
论文数: 0引用数: 0
h-index: 0
机构:
Merck KGaA, Darmstadt, GermanyRutgers State Univ, New Jersey Med Sch, Newark, NJ USA
Sylvester, E.
Hicking, C.
论文数: 0引用数: 0
h-index: 0
机构:
Merck KGaA, Darmstadt, GermanyRutgers State Univ, New Jersey Med Sch, Newark, NJ USA
Hicking, C.
Dangond, F.
论文数: 0引用数: 0
h-index: 0
机构:
EMD Serono Inc, Billerica, MA USARutgers State Univ, New Jersey Med Sch, Newark, NJ USA