CONCOMITANT INCREASE IN PUTRESCINE INCORPORATION WITH TRANSFERRIN UPTAKE INTO RAT RETICULOCYTES

被引：2
|
作者：
KATOH, S
ISHII, Y
OHBA, Y
KOHNO, H
OHKUBO, Y
机构：
[1] Department Of Radiopharmacy, Tohoku College Of Pharmacy, Sendai 981, 4—4-1, Komatsushima, Aoba-ku
来源：
CHEMICAL & PHARMACEUTICAL BULLETIN | 1992年 / 40卷 / 01期
关键词：
PUTRESCINE INCORPORATION; TRANSFERRIN UPTAKE; RETICULOCYTE; ENDOCYTOSIS;
D O I：
10.1248/cpb.40.258
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Concomitant increase in putrescine incorporation with transferrin uptake into rat reticulocytes was found. [C-14]Putrescine incorporation occurred in the presence of transferrin at 37-degrees-C. The subcellular distribution of incorporated [C-14]putrescine showed that the incorporation in the plasma membrane time dependently increased. Both I-125-labeled transferrin uptake and [C-14]putrescine incorporation decreased when ethylene glycol bis(2-aminoethyl ether)-N,N,N',N'-tetraacetic acid was added, while it increased with the addition of A23187.
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页码：258 / 260
页数：3
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