INFLUENCE OF NOCLOPROST ON THE VASCULAR-RESPONSES TO VARIOUS STIMULI IN THE ISOLATED PERFUSED RABBIT KIDNEY

被引：0
|
作者：
ERCAN, ZS [1 ]
TURKER, R [1 ]
机构：
[1] UNIV ANKARA,FAC MED,DEPT PHARMACOL,ANKARA,TURKEY
来源：
EXPERIENTIA | 1991年 / 47卷 / 01期
关键词：
NOCLOPROST; RABBIT KIDNEY; ANGIOTENSIN-II; NORADRENALINE; SYMPATHETIC STIMULATION;
D O I：
10.1007/BF02041256
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Nocloprost, a new synthetic prostanoid, elicited a vasodilator action when given through the renal artery of the isolated perfused rabbit kidney. Lower concentrations of the compound inhibited the pressor response to sympathetic stimulation or to angiotensin II, but potentiated the pressor effect of exogenous noradrenaline. These results were taken as an evidence that nocloprost prevents the release of neurotransmitter by a presynaptic mechanism.
引用
收藏
页码：69 / 70
页数：2
相关论文
共 50 条
  • [31] Renal vascular responses to high and low ionized calcium: Influence of norepinephrine in the isolated perfused rat kidney
    Kaufmann, MA
    Pargger, H
    Castelli, I
    Steiner, LA
    Drop, LJ
    JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE, 1996, 40 (01): : 110 - 115
  • [32] VASCULAR-RESPONSES TO ARACHIDONIC-ACID IN PERFUSED CANINE LUNG
    WICKS, TC
    ROSE, JC
    JOHNSON, M
    RAMWELL, PW
    KOT, PA
    CIRCULATION RESEARCH, 1976, 38 (03) : 167 - 171
  • [33] THE VASCULAR-RESPONSES OF THE ISOLATED PERFUSED BOVINE EXTERNAL EAR TO EXOGENOUS HISTAMINE AND 5-HT (SEROTONIN)
    EGHIANRUWA, KI
    EYRE, P
    VETERINARY RESEARCH COMMUNICATIONS, 1992, 16 (05) : 345 - 354
  • [34] VASCULAR-RESPONSES OF ISOLATED AND PERFUSED CANINE FEMORAL ARTERIES AND VEINS TO HISTAMINE, 2-PEA AND DIMAPRIT
    KAWAI, K
    CHIBA, S
    JAPANESE JOURNAL OF PHARMACOLOGY, 1987, 43 : P286 - P286
  • [35] EFFECT OF DETERGENT ON VASCULAR-RESPONSES TO NORADRENALINE IN ISOLATED PERFUSED GILLS OF THE EEL, ANGUILLA-ANGUILLA L
    STAGG, RM
    RANKIN, JC
    BOLIS, L
    ENVIRONMENTAL POLLUTION SERIES A-ECOLOGICAL AND BIOLOGICAL, 1981, 24 (01): : 31 - 37
  • [36] METABOLISM OF IODOTHYRONINES BY ISOLATED PERFUSED RABBIT KIDNEY
    RAMSDEN, DB
    WUSTEMAN, M
    PRINCE, HP
    BLACK, EG
    EVANS, AE
    PEGG, D
    HOFFENBERG, R
    CLINICAL SCIENCE AND MOLECULAR MEDICINE, 1978, 54 (02): : P35 - P35
  • [37] EXTRACTION OF GLUTATHIONE BY ISOLATED PERFUSED RABBIT KIDNEY
    FONTELES, MC
    PILLION, DJ
    JESKE, AH
    LEIBACH, FH
    JOURNAL OF SURGICAL RESEARCH, 1976, 21 (03) : 169 - 174
  • [38] NEPHROTOXICITY OF GENTAMICIN IN ISOLATED PERFUSED RABBIT KIDNEY
    BERTELLI, A
    GIOVANNINI, L
    PAPARELLI, A
    DRUGS UNDER EXPERIMENTAL AND CLINICAL RESEARCH, 1981, 7 (01) : 53 - 56
  • [39] INSULIN METABOLISM IN ISOLATED PERFUSED RABBIT KIDNEY
    PAGANO, G
    VERZETTI, G
    EMANUELLI, G
    BOLLETTINO DELLA SOCIETA ITALIANA DI BIOLOGIA SPERIMENTALE, 1972, 48 (07): : 164 - +
  • [40] EFFECTS OF PAF ANTAGONISTS ON RENAL VASCULAR ESCAPE AND TACHYPHYLAXIS IN THE ISOLATED PERFUSED RABBIT KIDNEY
    FONTELES, MC
    FERREIRA, MG
    PROSTAGLANDINS, 1988, 35 (05): : 827 - 827
12345