DIFFERENTIATION OF ENANTIOTOPIC CARBONYL GROUPS BY THE HORNER-WADSWORTH-EMMONS REACTION

被引：77
|
作者：
TANAKA, K
OHTA, Y
FUJI, K
TAGA, T
机构：
[1] KYOTO UNIV,INST CHEM RES,UJI,KYOTO 611,JAPAN
[2] KYOTO UNIV,FAC PHARMACEUT SCI,SAKYO KU,KYOTO 606,JAPAN
来源：
TETRAHEDRON LETTERS | 1993年 / 34卷 / 25期
关键词：
D O I：
10.1016/S0040-4039(00)60618-4
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A chiral phosphonoacetate 2 differentiates the enantiotopic carbonyl groups in an alpha-diketone 5 to afford the Z-olefin 6 in high yield and ee. The absolute stereochemistry of 6 was determined by X-ray analysis of 8 derived from 6.
引用
收藏
页码：4071 / 4074
页数：4
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