ALANINE AMINOTRANSFERASE;
ANTI-HEPATITIS C VIRUS;
CHRONIC HEPATITIS C;
DYNAMIC STUDY;
HEPATITIS C VIRUS RNA;
D O I:
10.1111/j.1440-1746.1994.tb01717.x
中图分类号:
R57 [消化系及腹部疾病];
学科分类号:
摘要:
The dynamics of alanine aminotransferase (ALT), anti-hepatitis C virus and hepatitis C virus (HCV) RNA in six cases with chronic HCV infection were studied for 3-7 years. Two of the six cases showed continued elevation of ALT, and three showed intermittent elevation. All cases were persistently positive for anti-HCV after initial seroconversion. Five of the six cases were persistently positive for HCV RNA detected by nested polymerase chain reaction, and one was positive intermittently. Thus hepatitis C virus replicates continually in a majority of patients with chronic hepatitis C, although some cases may show intermittent replication, and replication of hepatitis C virus does not always correlate with elevated ALT.