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Secondary Membranous Nephropathy Associated with Guillain-Barre Syndrome
被引:4
|作者:
Filippone, Edward J.
[1
,4
]
Kanzaria, Mitul
[1
]
Bell, Rodney
[2
]
Newman, Eric
[1
,4
]
Farber, John L.
[3
]
机构:
[1] Thomas Jefferson Univ, Dept Med, Philadelphia, PA 19107 USA
[2] Thomas Jefferson Univ, Dept Neurol, Philadelphia, PA 19107 USA
[3] Thomas Jefferson Univ, Dept Pathol, Philadelphia, PA 19107 USA
[4] Thomas Jefferson Univ, Div Nephrol, Philadelphia, PA 19107 USA
来源:
关键词:
Membranous nephropathy;
Nephrotic syndrome;
Guillain-Barre syndrome;
D O I:
10.1159/000350903
中图分类号:
R5 [内科学];
R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号:
1002 ;
100201 ;
摘要:
Membranous nephropathy (MN) is one of the most common causes of nephrotic syndrome (NS) in adults. It may be primary, usually mediated by IgG4 anti-phospholipase A2 autoanti-bodies or secondary to various other conditions. Guillain-Barre syndrome (GBS) has been associated with MN, but a cause and effect relation has not been proven. We present a case of concurrent development of GBS and severe NS, with renal biopsy demonstrating MN. IgG4 stain was negative, indicating that most likely, the MN was secondary and probably caused by the underlying GBS.
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页码:34 / 39
页数:6
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