This paper investigates what molecular biology has done for our understanding of the gene. I base a new account of the gene concept of classical genetics on the classical dogma that gene differences cause phenotypic differences. Although contemporary biologists often think of genes in terms of this concept, molecular biology provides a second way to understand genes. I clarify this second way by articulating a molecular gene concept. This concept unifies our understanding of the molecular basis of a wide variety of phenomena, including the phenomena that classical genetics explains in terms of gene differences causing phenotypic differences.
机构:
Univ Florida, Div Genet & Metab, Dept Pediat, Raymond C Philips Unit, Gainesville, FL 32605 USAUniv Florida, Div Genet & Metab, Dept Pediat, Raymond C Philips Unit, Gainesville, FL 32605 USA
Williams, Charles A.
Battaglia, Agatino
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机构:
Stella Maris Clin Res Inst Child & Adolescent Neu, I-256128 Pisa, ItalyUniv Florida, Div Genet & Metab, Dept Pediat, Raymond C Philips Unit, Gainesville, FL 32605 USA