Evaluation of Leptin Measurements in Newborns Born to Mothers with Vitamin D Deficiency

被引：0

作者：

Aslan, Nagehan ^{[1
]}

Pirgon, Ozgur ^{[2
]}

Sandal, Gonca ^{[3
]}

Dundar, Bumin ^{[4
]}

机构：

[1] Suleyman Demirel Univ, Tip Fak, Cocuk Sagligi & Hastaliklari ABD, Isparta, Turkey

[2] Suleyman Demirel Univ, Tip Fak, Cocuk Endokrin BD, Cocuk Sagligi & Hastaliklari ABD, Isparta, Turkey

[3] Suleyman Demirel Univ, Tip Fak, Yenidogan BD, Cocuk Sagligi & Hastaliklari ABD, Isparta, Turkey

[4] Katip Celebi Univ, Tip Fak, Cocuk Sagligi & Hastaliklari ABD, Cocuk Endokrin BD, Izmir, Turkey

来源：

JOURNAL OF CLINICAL AND ANALYTICAL MEDICINE | 2015年 / 6卷

关键词：

Vitamin D; Newborn; Leptin; Growth;

D O I：

10.4328/JCAM.3519

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Aim: In this study, we aimed to evaluate the leptin levels in newborns born to vitamin D deficient mothers (serum concentration of 25(OH) D was less than 20 ng/mL). Material and Method: Forty infants (22 infants born to vitamin D deficient mothers and age-matched 18 infants born to mothers with vitamin D sufficient) were enrolled the study. We measured 25(OH) D, calcium, phosphorus, parathormone, leptin, in each groups. Anthropometric data recorded for the newborns. Results: The mean vitamin D concentration of vitamin D deficient mothers was 8.7 +/- 3.4 ng/mL and vitamin D sufficient group was 26.7 +/- 4.0 ng/mL (p<0.001). There was no a significant difference between vitamin D deficient and sufficient mothers (p:0.299). Leptin levels of the newborns born to vitamin D deficient mothers lower than the sufficient mother group (0.83 +/- 0.6 vs. 2.7 +/- 5.2 pg/mL, p: 0.003). Discussion: Based on the findings of this study, we found lower leptin levels in infants born to vitamin D deficient mothers, however; this was no effect on neonatal anthropometric data.

引用

页码：452 / 455

页数：4

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