A PROGRAM TO CALCULATE THE ISOELECTRIC POINT OF MACROMOLECULES

被引：0
|
作者：
RIBEIRO, JM [1 ]
SILLERO, A [1 ]
机构：
[1] UNIV AUTONOMA MADRID,FAC MED,SCH MED,CSIC,INST INVEST BIOMED,DEPT BIOQUIM,E-28029 MADRID,SPAIN
来源：
COMPUTERS IN BIOLOGY AND MEDICINE | 1991年 / 21卷 / 03期
关键词：
BASIC INTERPRETERS; ISOELECTRIC POINT; MICROCOMPUTER PROGRAM; POLYNOMIAL FUNCTIONS;
D O I：
暂无
中图分类号：
Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
A program containing 260 sentences, written in BASIC and adapted to be run in personal computers, has been developed to calculate isoelectric point values of macromolecules (proteins, nucleic acids, polysaccharides, etc.). This implies the calculation of the coefficients and roots of a particular kind of polynomial. With common personal computers and using a compiled version of the program, the time required to calculate pI values of macromolecules containing for example, 9, 12, and 18 acid-base residues with different pK values was around 10 s, 2 min, and 2 h respectively.
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页码：131 / 141
页数：11
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