ANTIOXIDANT SYSTEMS AND ERYTHROCYTE LIFE-SPAN IN MAMMALS

被引:198
|
作者
KURATA, M
SUZUKI, M
AGAR, NS
机构
[1] GIFU UNIV, FAC AGR, DEPT VET MED, VET PHYSIOL LAB, GIFU 50111, JAPAN
[2] UNIV NEW ENGLAND, DEPT PHYSIOL, ARMIDALE, NSW 2351, AUSTRALIA
关键词
D O I
10.1016/0305-0491(93)90121-K
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
1. Erythrocyte antioxidant systems-superoxide dismutase (SOD), catalase (CAT), reduced glutathione (GSH), glutathione peroxidase (GSH-Px), glutathione S-transferase (GST) and glutathione reductase (GR)-were discussed in relation to fife-spans in some mammalian species. 2. The erythrocyte life-span of different mammals was found to be correlated with the levels of SOD, GSH-Px and GSH. 3. Data reviewed indicates that the erythrocyte life-span of each species is governed by both the oxygen radical formation and the efficiency of intrinsic antioxidant systems.
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页码:477 / 487
页数:11
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