NK AND LAK FUNCTIONS IN HUMAN CHRONIC CHAGAS-DISEASE

被引：1
|
作者：
STRACIERI, ABPL [1 ]
VOLTARELLI, JC [1 ]
机构：
[1] UNIV SAO PAULO,SCH MED,DEPT CLIN MED,BR-05508 SAO PAULO,BRAZIL
来源：
PARASITE IMMUNOLOGY | 1995年 / 17卷 / 07期
关键词：
CHAGAS DISEASE; KILLER CELLS;
D O I：
10.1111/j.1365-3024.1995.tb00905.x
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Natural killer (NK) and lymphokine-activated killer (LAK) functions were measured in 40 patients with chronic Chagas disease divided into asymptomatic/indeterminate (18) and symptomatic forms (22) and in 24 healthy controls. A chromium release assay was used employing K562 or P815 cell lines as targets. There was no difference in either NK or LAK activity between the three groups. A small number of patients in each group showed results above ol below the normal range for controls. However, there was no con elation between NK and LAK values in the same individual. rn conclusion, NK and LAK functions do not seem to be involved in the immunosuppression associated with human chronic Chagas disease.
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页码：381 / 383
页数：3
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