Technical determinants of success in catheter-directed thrombolysis for peripheral arterial occlusions

Local intraarterial thrombolytic therapy restores blood flow to the ischemic limb by dissolving the occlusive thrombus and identifies culprit lesions for treatment by means of surgical and/or percutaneous procedures. The techniques used for administration of the thrombolytic agent, the drug used, and the criteria for termination of the therapy are all factors that can influence both technical success and speed of lysis, This article discusses these factors and their influence on thrombolytic success.