A LAPLACE TRANSFORM TECHNIQUE FOR CALCULATING DIFFUSION TIME LAGS

被引：35

作者：

SIEGEL, RA ^{[1
]}

机构：

[1] UNIV CALIF SAN FRANCISCO,DEPT PHARMACEUT CHEM,SAN FRANCISCO,CA 94143

来源：

JOURNAL OF MEMBRANE SCIENCE | 1986年 / 26卷 / 03期

关键词：

DRUG PRODUCTS - Diffusion - MATHEMATICAL TRANSFORMATIONS - Laplace Transforms - MEMBRANES;

D O I：

10.1016/S0376-7388(00)82110-9

中图分类号：

TQ [化学工业];

学科分类号：

0817 ;

摘要：

A simple formula for diffusional time lags is derived for systems governed by linear equations with source terms. This formula is used to calculate the time lag for systems in which diffusion, dissolution and reversible or irreversible reactions occur. It is also shown that time lags can be calculated for nondiffusional systems. The application of time lags to pharmacokinetics is discussed in particular.

引用

页码：251 / 262

页数：12

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