The antiphospholipid syndrome in obstetrics represents a striking model of maternofetal pathology related to systemic and intraplacental thrombosis. Two pro-coagulant antibodies are now well known: lupus anticoagulant and anticardiolipin antibody. Therapy is preventive and efficient. It is based on a cautious choice from three drugs: aspirin, heparin, and corticosteroids.
机构:
Yale Univ, Dept Rheumatol, Sch Med, New Haven, CT 06520 USAYale Univ, Dept Rheumatol, Sch Med, New Haven, CT 06520 USA
George, Diane
Erkan, Doruk
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机构:
Cornell Univ, Weill Med Coll, Hosp Special Surg, Barbara Volcker Ctr Women & Rheumat Dis, New York, NY 10021 USAYale Univ, Dept Rheumatol, Sch Med, New Haven, CT 06520 USA
机构:
CUNY Mt Sinai Sch Med, Dept Med, Div Hematol, Thrombosis & Hemostasis Sect, New York, NY 10029 USACUNY Mt Sinai Sch Med, Dept Med, Div Hematol, Thrombosis & Hemostasis Sect, New York, NY 10029 USA