PREPARATION OF ENANTIOMERICALLY PURE HOMOPHENYLALANINE DERIVATIVES BY PALLADIUM-CATALYZED COUPLING REACTIONS

被引：0
|
作者：
FRASER, JL
JACKSON, RFW
PORTER, B
机构：
[1] UNIV NEWCASTLE UPON TYNE,DEPT CHEM,BEDSON BLDG,NEWCASTLE TYNE NE1 7RU,TYNE & WEAR,ENGLAND
[2] RHONE POULENC RORER LTD,DAGENHAM RES CTR,DAGENHAM RM10 7XS,ESSEX,ENGLAND
来源：
SYNLETT | 1994年 / 05期
关键词：
D O I：
暂无
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Reaction of the glutamic acid derived organozinc reagent 3 with aromatic iodides under palladium catalysis at 50-degrees-C gives homophenylalanine derivatives 5; conversion of adduct 5a to Z-homophenylalanine methyl ester 6 using LiOMe in methanol establishes the usefulness of this method for the preparation of homophenylalanine derivatives.
引用
收藏
页码：379 / 380
页数：2
相关论文
共 50 条
  • [41] Synthesis of enantiomerically pure (-)-wine lactone based on a palladium-catalyzed enantioselective allylic substitution
    Bergner, EJ
    Helmchen, G
    EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2000, 2000 (03) : 419 - 423
  • [42] Palladium-Catalyzed Reactions
    Della Ca, Nicola
    CATALYSTS, 2021, 11 (05)
  • [43] Palladium-Catalyzed Coupling Reactions: Carbonylative Heck Reactions To Give Chalcones
    Wu, Xiao-Feng
    Neumann, Helfried
    Beller, Matthias
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2010, 49 (31) : 5284 - 5288
  • [44] Palladium-Catalyzed Suzuki-Miyaura Coupling Reactions of Boronic Acid Derivatives with Aryl Chlorides
    Zhou, Zihong
    Zhang, Yaqi
    Xia, Wang
    Chen, Huixuan
    Liang, Hao
    He, Xuefeng
    Yu, Sifan
    Cao, Rihui
    Qiu, Liqin
    ASIAN JOURNAL OF ORGANIC CHEMISTRY, 2016, 5 (10) : 1260 - 1268
  • [45] Syntheses of 5-arylpyrazole derivatives via palladium-catalyzed cross-coupling reactions
    Yagi, K
    Ogura, T
    Numata, A
    Ishii, S
    Arai, K
    HETEROCYCLES, 1997, 45 (08) : 1463 - 1466
  • [46] Palladium-catalyzed coupling of tetraphenylbismuth(V) derivatives with methyl acrylate
    Gushchin, A. V.
    Malysheva, Yu. B.
    Kosov, D. Yu.
    Sharutin, V. V.
    RUSSIAN JOURNAL OF GENERAL CHEMISTRY, 2006, 76 (08) : 1253 - 1255
  • [47] Palladium-catalyzed coupling of tetraphenylbismuth(V) derivatives with methyl acrylate
    A. V. Gushchin
    Yu. B. Malysheva
    D. Yu. Kosov
    V. V. Sharutin
    Russian Journal of General Chemistry, 2006, 76 : 1253 - 1255
  • [48] SYNTHESIS OF ANTHRAQUINONE DERIVATIVES BY PALLADIUM-CATALYZED COUPLING OF TRIFLATES WITH STANNANES
    TAMAYO, N
    ECHAVARREN, AM
    PAREDES, MC
    FARINA, F
    NOHEDA, P
    TETRAHEDRON LETTERS, 1990, 31 (36) : 5189 - 5192
  • [49] Palladium-catalyzed carbonylation and coupling reactions of aryl chlorides and amines
    Perry, RJ
    Wilson, BD
    JOURNAL OF ORGANIC CHEMISTRY, 1996, 61 (21): : 7482 - 7485
  • [50] PALLADIUM-CATALYZED CARBON-CARBON COUPLING REACTIONS WITH TETRAARYLBORATES
    CATELLANI, M
    CHIUSOLI, GP
    FORNASARI, V
    GAZZETTA CHIMICA ITALIANA, 1990, 120 (12): : 779 - 781
12345