PREPARATION OF ENANTIOMERICALLY PURE HOMOPHENYLALANINE DERIVATIVES BY PALLADIUM-CATALYZED COUPLING REACTIONS

被引：0
|
作者：
FRASER, JL
JACKSON, RFW
PORTER, B
机构：
[1] UNIV NEWCASTLE UPON TYNE,DEPT CHEM,BEDSON BLDG,NEWCASTLE TYNE NE1 7RU,TYNE & WEAR,ENGLAND
[2] RHONE POULENC RORER LTD,DAGENHAM RES CTR,DAGENHAM RM10 7XS,ESSEX,ENGLAND
来源：
SYNLETT | 1994年 / 05期
关键词：
D O I：
暂无
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Reaction of the glutamic acid derived organozinc reagent 3 with aromatic iodides under palladium catalysis at 50-degrees-C gives homophenylalanine derivatives 5; conversion of adduct 5a to Z-homophenylalanine methyl ester 6 using LiOMe in methanol establishes the usefulness of this method for the preparation of homophenylalanine derivatives.
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页码：379 / 380
页数：2
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