REACTION OF QUINAZOLINE-2,4(1H,3H)-DIONE WITH N-SUBSTITUTED CYCLIC AMINES IN COMBINATION WITH PHOSPHORYL TRICHLORIDE

被引：4
|
作者：
YOSHIDA, K
TANAKA, T
OHTAKA, H
机构：
来源：
JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1991年 / 05期
关键词：
D O I：
10.1039/p19910001279
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The reaction of quinazoline-2,4(1H,3H)-dione with N-allyl, N-benzyl and N-methyl cyclic amines in combination with phosphoryl trichloride in the presence of tripropylamine in 1,4-dioxane afforded 4-chloro-2-(cycloalkylamino)quinazolines. In the case of N-substituted pyrrolidines, 4-chloro-2-(N-substituted 4-chlorobutylamino) quinazolines were also obtained.
引用
收藏
页码：1279 / 1282
页数：4
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