The Effects of Statins on Renal Functions

被引：0
|
作者：
Cavdar, Caner y [1 ]
Gungor, Ozkan [2 ]
Camsari, Taner [1 ]
机构：
[1] Dokuz Eylul Univ, Tip Fak, Ic Hastaliklari AD, Nefrol BD, Izmir, Turkey
[2] Dokuz Eylul Univ, Tip Fak, Ic Hastaliklari AD, Izmir, Turkey
来源：
TURKISH NEPHROLOGY DIALYSIS AND TRANSPLANTATION JOURNAL | 2005年 / 14卷 / 03期
关键词：
statins; dislypidemia; renal functions;
D O I：
暂无
中图分类号：
R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];
学科分类号：
1002 ; 100201 ;
摘要：
Lipid metabolism disorder results in progression of chronic renal disease. Statins inhibit HMG-CoA reductase, that catalyzes the rate-limiting step in cholesterol biosynthesis and statins also decrease clinical risks related with atherosclerosis. In addition to lipid-lowering effects, a multitude of potentially renal protective effects are being ascribed to statins in recent reports, including improved endothelial function, increased plaque stability, decreased monocyte migration, decreased mesengial matrix proliferation, and improved circulation. In this review, the pathogenesis of beneficial effect of statins are well examined and we present the reports which were investigated the effects of statins on renal functions.
引用
收藏
页码：104 / 107
页数：4
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