TREATMENT AND PROGNOSIS OF METASTATIC GESTATIONAL TROPHOBLASTIC DISEASE

被引:2
|
作者
PUNNONEN, R [1 ]
HORI, A [1 ]
OKAWADA, M [1 ]
KUDOH, R [1 ]
机构
[1] SAPPORO MED COLL, DEPT OBSTET & GYNECOL, SAPPORO, HOKKAIDO 060, JAPAN
关键词
D O I
10.3109/00016348409155520
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Three cases with metastasized choriocarcinoma are reported. The basic chemotherapeutic regimen was methotrexate and actinomycin D, combined with cyclophosphamide or vinblastine. Surgery was used in the treatment of both primary and metastatic lesions. The chief indications for hysterectomy arise when chemotherapy has obviously failed. Thoracotomy was performed for a pulmonary metastasis and nephrectomy for a metastasis of the kidney. Craniotomy was performed to control the brain hemorrhage. Aggressive multidrug chemotherapy is considered necessary as the primary treatment for high-risk cases of trophoblastic disease.
引用
收藏
页码:299 / 302
页数:4
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