A 67 year old woman first developed left-sided sensorimotor seizures postoperatively in association with infection and mild hyponatraemia. She was found to have previously unrecognized tuberous sclerosis, with gross pathognomic features: periungual fibromata, facial angiofibromata, calcified subependymal nodules, cortical tubers and multiple renal angiomyolipomata. Her son who was epileptic was also found to have other mild features of tuberous sclerosis as a result. As far as we are aware our patient is the oldest for the first presentation of tuberous sclerosis.
机构:
Washington Univ, Sch Med, Dept Neurol, St Louis, MO 63110 USAUniv Penn, Dept Neurol, Penn Epilepsy Ctr, Perelman Sch Med, Philadelphia, PA 19104 USA
Wong, Michael
Crino, Peter B.
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Univ Penn, Dept Neurol, Penn Epilepsy Ctr, Perelman Sch Med, Philadelphia, PA 19104 USAUniv Penn, Dept Neurol, Penn Epilepsy Ctr, Perelman Sch Med, Philadelphia, PA 19104 USA
机构:
Fdn Adolphe De Rothschild, Unite Neurochirurg Infantile, F-75019 Paris, FranceFdn Adolphe De Rothschild, Unite Neurochirurg Infantile, F-75019 Paris, France
Fohlen, Martine
Bulteau, Christine
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Fdn Adolphe De Rothschild, Unite Neurochirurg Infantile, F-75019 Paris, FranceFdn Adolphe De Rothschild, Unite Neurochirurg Infantile, F-75019 Paris, France
Bulteau, Christine
Jalin, Claude
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Fdn Adolphe De Rothschild, Unite Neurochirurg Infantile, F-75019 Paris, FranceFdn Adolphe De Rothschild, Unite Neurochirurg Infantile, F-75019 Paris, France
Jalin, Claude
Dorfmueller, Georg
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Fdn Adolphe De Rothschild, Unite Neurochirurg Infantile, F-75019 Paris, FranceFdn Adolphe De Rothschild, Unite Neurochirurg Infantile, F-75019 Paris, France
Dorfmueller, Georg
Delalande, Olivier
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Fdn Adolphe De Rothschild, Unite Neurochirurg Infantile, F-75019 Paris, FranceFdn Adolphe De Rothschild, Unite Neurochirurg Infantile, F-75019 Paris, France
机构:
Massachusetts Gen Hosp, Dept Neurol, Carol & James Herscot Ctr TSC, Boston, MA 02114 USAMassachusetts Gen Hosp, Dept Neurol, Carol & James Herscot Ctr TSC, Boston, MA 02114 USA