Systems Biology Application in Research on Sustainable Utilization of Chinese Materia Medica Resources

被引：2
|
作者：
Wang, Sheng [1 ]
Xu, Hai-yu [1 ]
Guo, Lan-ping [1 ]
Huang, Lu-qi [1 ]
Liu, Chang-xiao [2 ]
机构：
[1] China Acad Chinese Med Sci, State Key Lab Breeding Base Dao Di Herbs, Natl Resource Ctr Chinese Mat Med, Beijing 100700, Peoples R China
[2] Tianjin Inst Pharmaceut Res, Tianjin Binhai Res Ctr Food & Drug Regulatory Sci, Tianjin Ctr New Drug Evaluat Res, Tianjin 300193, Peoples R China
来源：
CHINESE HERBAL MEDICINES | 2015年 / 7卷 / 03期
基金：
中国国家自然科学基金;
关键词：
biosynthesis; breeding design; Chinese materia medica; evaluation; identification; metabolic engineering; synthetic biology; systems biology;
D O I：
10.1016/S1674-6384(15)60042-9
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
This paper reviews the progress of systems biology applied to researching on sustainable utilization of Chinese materia medica (CMM) resources in the following aspects: identification and evaluation of CMM resources, analysis of biosynthesis and their regulation of active ingredients in medicinal plants, metabolic engineering and synthetic biology research of medicinal plants, and molecular breeding of medicinal plants. Development of systems biology is currently leading to extremely broad applications in the field of CMM resources, and systems biology will become a significant approach for the sustainable utilization of CMM resources.
引用
收藏
页码：196 / 203
页数：8
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