CRYSTAL-STRUCTURE AT 3.5 ANGSTROM RESOLUTION OF HIV-1 REVERSE-TRANSCRIPTASE COMPLEXED WITH AN INHIBITOR (SCIENCE, VOL 256, PG 1783, 1992)

被引：0

作者：

STEITZ, TA ^{[1
]}

KOHLSTAEDT, LA ^{[1
]}

WANG, J ^{[1
]}

FRIEDMAN, JM ^{[1
]}

RICE, PA ^{[1
]}

机构：

[1] YALE UNIV,DEPT MOLEC BIOPHYS & BIOCHEM & CHEM,NEW HAVEN,CT 06511

来源：

SCIENCE | 1993年 / 259卷 / 5093期

关键词：

D O I：

10.1126/science.259.5093.295

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

引用

页码：295 / 295

页数：1

共 36 条

[31] Crystal Structure of tert-Butyldimethylsilyl-spiroaminooxathioledioxide-thymine (TSAO-T) in Complex with HIV-1 Reverse Transcriptase (RT) Redefines the Elastic Limits of the Non-nucleoside Inhibitor-Binding Pocket
Das, Kalyan
Bauman, Joseph D.
Rim, Angela S.
Dharia, Chhaya
Clark, Arthur D., Jr.
Camarasa, Maria-Jose
Balzarini, Jan
Arnold, Eddy
JOURNAL OF MEDICINAL CHEMISTRY, 2011, 54 (08) : 2727 - 2737
[32] Efficacy and safety of nucleoside reverse transcriptase inhibitor-sparing salvage therapy for multidrug-resistant HIV-1 infection based on new-class and new-generation antiretrovirals (vol 66, pg 358, 2011)
Imaz, Arkaitz
Llibre, Josep M.
Mora, Marta
Mateo, Gracia
Camacho, Angela
Blanco, Jose R.
Curran, Adrian
Santos, Jose R.
Caballero, Estrella
Bravo, Isabel
Gaya, Francisco
Domingo, Pere
Rivero, Antonio
Falco, Vincenc
Clotet, Bonaventura
Ribera, Esteban
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2011, 66 (09) : 2194 - 2194
[33] Urea-PETT compounds as a new class of HIV-1 reverse transcriptase inhibitors.: 3.: Synthesis and further structure-activity relationship studies of PETT analogues. (vol 42, pg 4145, 1999)
Högberg, M
Sahlberg, C
Engelhardt, P
Noréen, R
Kangasmetsä, J
Johansson, NG
Öberg, B
Vrang, L
Zhang, H
Sahlberg, BL
Unge, T
Lövgren, S
Fridborg, K
Bäckbro, K
JOURNAL OF MEDICINAL CHEMISTRY, 2000, 43 (02) : 304 - 304
[34] Simple, short peptide derivatives of a sulfonylindolecarboxamide (L-737,126) active in vitro against HIV-1 wild type and variants carrying non-nucleoside reverse transcriptase inhibitor resistance mutations. (vol 47, pg 3892, 2004)
Silvestri, R
Artico, M
De Martino, G
La Regina, G
Loddo, R
La Colla, M
Mura, M
La Colla, P
JOURNAL OF MEDICINAL CHEMISTRY, 2004, 47 (22) : 5592 - 5592
[35] Crystal structure of chemically synthesized HIV-1 protease and a ketomethylene isostere inhibitor based on the p2/NC cleavage site (Reprinted from Bioorg. Med. Chem. Lett., vol 18, pg 4554-4557, 2008)
Torbeev, Vladimir Yu.
Mandal, Kalyaneswar
Terechko, Valentina A.
Kent, Stephen B. H.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2008, 18 (22) : 6012 - 6015
[36] Dual treatment with lopinavir-ritonavir plus lamivudine versus triple treatment with lopinavir-ritonavir plus lamivudine or emtricitabine and a second nucleos(t)ide reverse transcriptase inhibitor for maintenance of HIV-1 viral suppression (OLE): a randomised, open-label, non-inferiority trial (vol 15, pg 785, 2015)
Arribas, Jose R.
Girard, Pierre-Marie
Landman, Roland
LANCET INFECTIOUS DISEASES, 2015, 15 (08): : 875 - 875

← 1 2 3 4 →