UV-SPECTROPHOTOMETRIC METHOD FOR ESTIMATION OF SECNIDAZOLE IN BULK AND TABLET DOSAGE FORM

被引：2

作者：

Sonpetkar, Jinendra M. ^{[1
]}

Joshi, Deval V. ^{[1
]}

Patel, Nakul B. ^{[1
]}

Wagdarikar, Mansi J. ^{[1
]}

机构：

[1] Indira Coll Pharm, New Mumbai Pune Highway, Pune 411041, Maharashtra, India

来源：

INTERNATIONAL JOURNAL OF PHARMACEUTICAL SCIENCES AND RESEARCH | 2012年 / 3卷 / 02期

关键词：

Secnidazole; Methanol: Double distilled water (30:70); UV-Visible Spectrophotometer;

D O I：

10.13040/IJPSR.0975-8232.3(2).536-38

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

A simple, precise and accurate UV-Spectrophotometric method has been developed and validated for estimation of secnidazole in bulk and tablet dosage form. It shows maximum absorbance at 313 nm with methanol and water (30: 70). Estimation was carried out by A(1%1cm) and by comparison with standard. Calibration graph was found to be linear (r(2) =0.09998) over concentration range of 1-4 mu g/ml. The proposed methods appear to be simple, sensitive, and reproducible when checked for parameters like accuracy, precision, limit of detection for routine determination of secnidazole in bulk as well as in tablet. The methods can be adopted in its routine analysis.

引用

页码：536 / 538

页数：3

共 50 条

[41] Spectrophotometric estimation of propranolol in tablet dosage form
Bhandari, Anil
Kumar, Brijesh
Patel, Rakesh
ASIAN JOURNAL OF CHEMISTRY, 2008, 20 (01) : 802 - 804
[42] Spectrophotometric estimation of nisoldipine in tablet dosage form
Al Bratty, Mohammed
INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH AND ALLIED SCIENCES, 2016, 5 (03): : 157 - 163
[43] Spectrophotometric estimation of Tadalafil in tablet dosage form
Mukesh, Mohite
Lata, Kothapalli
Asha, Thomas
Sumitra, Jangam
Avinash, Deshpande
INDIAN JOURNAL OF PHARMACEUTICAL EDUCATION AND RESEARCH, 2007, 41 (03) : 270 - 273
[44] DEVELOPMENT AND VALIDATION OF UV VISIBLE SPECTROPHOTOMETRIC METHOD FOR ESTIMATION OF ACECLOFENAC AND TRAMADOL IN BULK AND DOSAGE FORM
Mali, Suresh
Ahmad, Sufiyan
Shastry, V. M.
INTERNATIONAL JOURNAL OF PHARMACEUTICAL SCIENCES AND RESEARCH, 2018, 9 (09): : 3852 - 3857
[45] DEVELOPMENT OF DIFFERENCE SPECTROPHOTOMETRIC METHOD FOR THE ESTIMATION OF LEFLUNOMIDE IN TABLET DOSAGE FORM
Prabu, S. Lakshmana
Prakash, T. N. K. Suriya
Shanmugarathinam, A.
CHEMICAL INDUSTRY & CHEMICAL ENGINEERING QUARTERLY, 2012, 18 (03) : 407 - 410
[46] DEVELOPMENT AND VALIDATION OF SPECTROPHOTOMETRIC METHOD FOR THE ESTIMATION OF RITONAVIR IN TABLET DOSAGE FORM
Trivedi, C. D.
Mardia, R. B.
Suhagia, B. N.
Chauhan, S. P.
INTERNATIONAL JOURNAL OF PHARMACEUTICAL SCIENCES AND RESEARCH, 2013, 4 (12): : 4567 - 4572
[47] Development and Validation of the UV Spectrophotometric Method for Simultaneous Determination of Paracetamol and Pseudoephedrine in Bulk and Combined Tablet Dosage Form
Ali, Mohamed S.
Elsaman, Tilal
PHARMACEUTICAL CHEMISTRY JOURNAL, 2021, 54 (12) : 1306 - 1310
[48] Development and Validation of the UV Spectrophotometric Method for Simultaneous Determination of Paracetamol and Pseudoephedrine in Bulk and Combined Tablet Dosage Form
Mohamed S. Ali
Tilal Elsaman
Pharmaceutical Chemistry Journal, 2021, 54 : 1306 - 1310
[49] UV Spectrophotometric and Stability Indicating RP-HPLC Assay Methods for the Estimation of Etodolac in Bulk and Tablet Dosage Form
Biswal, Sabyasachi
Mondal, Sumanta
Mondal, Prasenjit
INTERNATIONAL JOURNAL OF PHARMACEUTICAL INVESTIGATION, 2019, 9 (02) : 53 - 58
[50] NEW SPECTROPHOTOMETRIC METHODS FOR ESTIMATION OF ANASTRAZOLE BULK AND TABLET DOSAGE FORM BY DERIVATIVE SPECTROSCOPY
Sharma, M. C.
Sharma, Smita
JOURNAL OF OPTOELECTRONIC AND BIOMEDICAL MATERIALS, 2010, 2 (04): : 197 - 201

← 1 2 3 4 5 →