The androgen receptor and clinical challenges

被引:0
|
作者
Payne, Heather A. [1 ]
Sedelaar, Michiel [2 ]
Jones, Rob [3 ]
机构
[1] Univ Coll Hosp, London, England
[2] Radboud Univ Nijmegen, Nijmegen Med Ctr, Nijmegen, Netherlands
[3] Univ Glasgow, Med Oncol, Beatson West Scotland Canc Ctr, Glasgow, Lanark, Scotland
关键词
D O I
10.1002/tre.390
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
This report is based on a seminar held during the 10th Annual Meeting of the British Uro-oncology Group in London, 13-14 September 2013. The seminar focused on all aspects of the role of the androgen receptor in prostate cancer, from an overview of the molecular mechanisms and underlying pathways to the development of therapeutic agents designed to inhibit the androgen receptor.
引用
收藏
页码:39 / 42
页数:4
相关论文
共 50 条
  • [41] Molecular features and clinical phenotypes in androgen insensitivity syndrome in the absence and presence of androgen receptor gene mutations
    Holterhus, PM
    Werner, R
    Hoppe, U
    Bassler, J
    Korsch, E
    Ranke, MB
    Dörr, HG
    Hiort, O
    JOURNAL OF MOLECULAR MEDICINE-JMM, 2005, 83 (12): : 1005 - 1013
  • [42] A pilot for searching androgen receptor mutations in Turkish male pseudohermaphrodites with clinical diagnosis of androgen insensitivity syndrome
    Akcay, Teoman
    Guran, Tulay
    Turan, Serap
    Sevinc, Deniz
    Ulucan, Korkut
    Guney, Ilter
    Aras, Bekir
    Adal, Erdal
    Bereket, Abdullah
    HORMONE RESEARCH, 2008, 70 : 249 - 249
  • [43] Therapies Targeted to Androgen Receptor Signaling Axis in Prostate Cancer: Progress, Challenges, and Hope
    Saranyutanon, Sirin
    Srivastava, Sanjeev Kumar
    Pai, Sachin
    Singh, Seema
    Singh, Ajay Pratap
    CANCERS, 2020, 12 (01)
  • [44] Androgen Receptor in Breast Cancer-Clinical and Preclinical Research Insights
    Anestis, Aristomenis
    Zoi, Ilianna
    Papavassiliou, Athanasios G.
    Karamouzis, Michalis V.
    MOLECULES, 2020, 25 (02):
  • [45] The effect of androgen receptor expression on clinical characterization of metastatic breast cancer
    Kim, Ji-Yeon
    Park, Kyunghee
    Lee, Eunjin
    Jung, Hae Hyun
    Ahn, Jin Seok
    Im, Young-Hyuck
    Park, Woong-Yang
    Park, Yeon Hee
    ONCOTARGET, 2017, 8 (05) : 8693 - 8706
  • [46] Tissue selective androgen receptor modulators (SARMs): A path to a clinical candidate
    Chekler, Eugene
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2015, 250
  • [47] Is phosphorylation of the androgen receptor of clinical significance in the development and progression of prostate cancer
    Adams, C.
    McCall, P.
    Edwards, J.
    EUROPEAN JOURNAL OF MEDICAL RESEARCH, 2010, 15 : 155 - 155
  • [48] Expression of estrogen receptors and androgen receptor and their clinical significance in gastric cancer
    Tang, Wenbo
    Liu, Rujiao
    Yan, Yan
    Pan, Xiaoli
    Wang, Minjun
    Han, Xiaotian
    Ren, Hui
    Zhang, Zhe
    ONCOTARGET, 2017, 8 (25) : 40765 - 40777
  • [49] ANDROGEN RECEPTOR GENE AND ITS CLINICAL IMPORTANCE IN GYNECOLOGY, ONCOLOGY AND INFERTILITY
    Sarikaya, Esma
    Gungor, Tayfun
    Ozaksit, Gulnur
    Mollamahmutoglu, Leyla
    MARMARA MEDICAL JOURNAL, 2010, 23 (02): : 316 - 322
  • [50] KENNEDY'S DISEASE Clinical Significance of Tandem Repeats in the Androgen Receptor
    Zajac, Jeffrey A.
    Mark Ng Tang Fui
    TANDEM REPEAT POLYMORPHISMS: GENETIC PLASTICITY, NEURAL DIVERSITY AND DISEASE, 2012, 769 : 153 - 168