A NEW CLASS OF HERBICIDE WHICH INHIBITS ACETYL-COA CARBOXYLASE IN SENSITIVE PLANT-SPECIES

被引：14

作者：

WALKER, KA ^{[1
]}

RIDLEY, SM ^{[1
]}

LEWIS, T ^{[1
]}

HARWOOD, JL ^{[1
]}

机构：

[1] ICI AGROCHEM, JEALOTTS HILL RES STN, BRACKNELL RG12 6CY, BERKS, ENGLAND

来源：

PHYTOCHEMISTRY | 1990年 / 29卷 / 12期

关键词：

3-isopropyl-6-(N-[2,2-dimethylpropyl]-acetamido-1,3,5triazine-2,4,-(1H, 3H)dione; Acetyl-CoA carboxylase; graminicides; herbicide; inhibition;

D O I：

10.1016/0031-9422(90)85324-9

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A new class of compound, PP600 (3-isopropyl-6-(N-[2,2-dimethylpropyl]-acetamido-1,3,5-triazine-2,4-(1H, 3H)dione) has been found which inhibits the formation of the acyl lipids in sensitive plant species. Experiments using radiolabelled precursors showed clearly that PP600 inhibited de novo fatty acid synthesis at the level of acetyl-CoA carboxylase. However, unlike the cyclohexanediones and aryloxyphenoxy propionate herbicides which also show a similar action, PP600 was active at lower concentrations in vivo than in enzyme incubations, suggesting that it may be metabolised to a more active compound in sensitive grass species. © 1990.

引用

页码：3743 / 3747

页数：5

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