THE ROLE OF PREGNANCY IN THE COURSE AND ETIOLOGY OF RHEUMATOID-ARTHRITIS

被引:146
|
作者
DASILVA, JAP [1 ]
SPECTOR, TD [1 ]
机构
[1] ST BARTHOLOMEWS HOSP, DEPT RHEUMATOL, CHARTERHOUSE SQ, LONDON EC1M 6BQ, ENGLAND
基金
英国惠康基金;
关键词
D O I
10.1007/BF02207955
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The aetiology of rheumatoid arthritis (RA) is unknown, although being female is generally recognized as the most important independent risk factor, the disease being 2 to 3 times more frequent in females than in males. The dramatic effect of pregnancy in rheumatoid arthritis has been documented for over 50 years. This review examines the evidence and possible mechanisms by which pregnancy modifies the disease process and may alter predisposition to the development of RA in later life.
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页码:189 / 194
页数:6
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