A NEW ROUTE FOR THE SYNTHESIS OF 2-AMINOPYRIDINES

被引：0
|
作者：
Kibou, Zahira [1 ]
Cheikh, Nawel [1 ]
Choukchou-Braham, Noureddine [1 ]
Mostefa-Kara, Bachir [1 ]
Benabdellah, Mohammed [1 ]
Villemin, Didier [2 ]
机构：
[1] Univ Tlemcen, Fac Sci, Dept Chim, Lab Catalyse & Synth Chim Organ, BP 119, Tilimsen 13000, Algeria
[2] ENSICAEN, LCMT, UMR CNRS 6507, F-14050 Caen, France
来源：
SCIENTIFIC STUDY AND RESEARCH-CHEMISTRY AND CHEMICAL ENGINEERING BIOTECHNOLOGY FOOD INDUSTRY | 2011年 / 12卷 / 02期
关键词：
2-amino-3-cyanopyridines; enaminonitriles; green chemistry; microwave; solvent-free;
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The 2-aminopyridines constitute a very large class ofnitrogen heterocycles, which have a great biological activity, such as the antibacterial, anti-inflammatory and analgesics activity, as well as the 2-amino-4-(4-chlorophenyl)-5-oxo-5,6,7,8-tetrahydroquinoline-3-carbonitrile has a antifungal activity. A new approach of synthesis of 2-amino-3cyanopyridines was developed in our laboratory, based on the condensation of the intermediary of enaminonitrile with different primary amines in solvent-free environments.
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页码：121 / 126
页数：6
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