RISK ESTIMATES - PAST, PRESENT, AND FUTURE

被引:2
|
作者
ABRAHAMSON, S
机构
[1] Radiation Effects Research Foundation, Hiroshima, 732
[2] Department of Zoology, University of Wisconsin, Madison, WI
来源
HEALTH PHYSICS | 1990年 / 59卷 / 01期
关键词
D O I
10.1097/00004032-199007000-00011
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
Risk estimates for genetic disease developed over the past 30 yhave been reviewed. The influence of dose rate and nonlinear dose-response curves on low dose estimates are discussed, and a reevaluation of doubling dose from acute irradiation is presented. The issue of differential sensitivity between human and mouse data are discussed with respect to the lack of an observable induced mutation rate in the offspring of A-bomb survivors. It is concluded that the “presumably” more sensitive mouse-derived risk estimates would not predict a significant increase in Fi abnormalities in humans. Therefore, it may be premature to accept the interpretation that man is less radiosensitive than the mouse. © 1990 Health Physics Society Pergamon Press plc.
引用
收藏
页码:99 / 102
页数:4
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