In order to characterize the appearances of bronchiolitis obliterans on high-resolution CT (HRCT) and to relate the extent of HRCT abnormalities to pulmonary function tests, the HRCT scans of 18 patients with bronchiolitis obliterans were examined by two independent observers. The underlying causes for the development of bronchiolitis obliterans were penicillamine therapy (n = 5), previous infection (n = 4), graft-vs-host disease (n = 3), and miscellaneous causes (n = 6). Abnormal HRCT findings were present in all cases. The commonest HRCT abnormalities consisted of patchy areas of decreased parenchymal attenuation (n = 15), subsegmental (n = 12) and segmental (n = 6) bronchial dilatation and centrilobular branching structures (n = 5). There was no significant correlation between the extent of abnormalities and the static lung volumes or the impairment in gas transfer (all P values > 0.05). The only significant correlation was between the number of segments with subsegmental bronchial dilatation and the forced expiratory volume in one second (Wilcoxon r = 0.61, P < 0.01). We conclude that the great majority of patients with bronchiolitis obliterans have HRCT abnormalities. However, there is poor correlation between the extent of abnormalities on HRCT and functional impairment.
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YOKOHAMA CITY UNIV, SCH MED, DEPT INTERNAL MED 1, KANAZAWA KU, YOKOHAMA 236, JAPANYOKOHAMA CITY UNIV, SCH MED, DEPT INTERNAL MED 1, KANAZAWA KU, YOKOHAMA 236, JAPAN
WATANUKI, Y
SUZUKI, S
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YOKOHAMA CITY UNIV, SCH MED, DEPT INTERNAL MED 1, KANAZAWA KU, YOKOHAMA 236, JAPANYOKOHAMA CITY UNIV, SCH MED, DEPT INTERNAL MED 1, KANAZAWA KU, YOKOHAMA 236, JAPAN
SUZUKI, S
NISHIKAWA, M
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YOKOHAMA CITY UNIV, SCH MED, DEPT INTERNAL MED 1, KANAZAWA KU, YOKOHAMA 236, JAPANYOKOHAMA CITY UNIV, SCH MED, DEPT INTERNAL MED 1, KANAZAWA KU, YOKOHAMA 236, JAPAN
NISHIKAWA, M
MIYASHITA, A
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YOKOHAMA CITY UNIV, SCH MED, DEPT INTERNAL MED 1, KANAZAWA KU, YOKOHAMA 236, JAPANYOKOHAMA CITY UNIV, SCH MED, DEPT INTERNAL MED 1, KANAZAWA KU, YOKOHAMA 236, JAPAN
MIYASHITA, A
OKUBO, T
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YOKOHAMA CITY UNIV, SCH MED, DEPT INTERNAL MED 1, KANAZAWA KU, YOKOHAMA 236, JAPANYOKOHAMA CITY UNIV, SCH MED, DEPT INTERNAL MED 1, KANAZAWA KU, YOKOHAMA 236, JAPAN
机构:
Sungkyunkwan Univ, Sch Med, Samsung Med Ctr, Dept Radiol, Seoul 135710, South Korea
Sungkyunkwan Univ, Sch Med, Samsung Med Ctr, Ctr Imaging Sci, Seoul 135710, South KoreaSungkyunkwan Univ, Sch Med, Samsung Med Ctr, Dept Radiol, Seoul 135710, South Korea
Song, Jong Woon
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Koh, Won-Jung
Lee, Kyung Soo
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Sungkyunkwan Univ, Sch Med, Samsung Med Ctr, Ctr Imaging Sci, Seoul 135710, South KoreaSungkyunkwan Univ, Sch Med, Samsung Med Ctr, Dept Radiol, Seoul 135710, South Korea
Lee, Kyung Soo
Lee, Ji Young
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Sungkyunkwan Univ, Sch Med, Samsung Med Ctr, Dept Radiol, Seoul 135710, South Korea
Sungkyunkwan Univ, Sch Med, Samsung Med Ctr, Ctr Imaging Sci, Seoul 135710, South KoreaSungkyunkwan Univ, Sch Med, Samsung Med Ctr, Dept Radiol, Seoul 135710, South Korea
Lee, Ji Young
Chung, Myung Jin
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Sungkyunkwan Univ, Sch Med, Samsung Med Ctr, Dept Radiol, Seoul 135710, South Korea
Sungkyunkwan Univ, Sch Med, Samsung Med Ctr, Ctr Imaging Sci, Seoul 135710, South KoreaSungkyunkwan Univ, Sch Med, Samsung Med Ctr, Dept Radiol, Seoul 135710, South Korea
Chung, Myung Jin
Kim, Tale Sung
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Sungkyunkwan Univ, Sch Med, Samsung Med Ctr, Dept Radiol, Seoul 135710, South KoreaSungkyunkwan Univ, Sch Med, Samsung Med Ctr, Dept Radiol, Seoul 135710, South Korea
Kim, Tale Sung
Kwon, O. Jung
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Sungkyunkwan Univ, Sch Med, Samsung Med Ctr, Div Pulm & Crit Care Med,Dept Med, Seoul 135710, South KoreaSungkyunkwan Univ, Sch Med, Samsung Med Ctr, Dept Radiol, Seoul 135710, South Korea