BRONCHIOLITIS OBLITERANS - HIGH-RESOLUTION CT FINDINGS AND CORRELATION WITH PULMONARY-FUNCTION TESTS

被引:104
|
作者
PADLEY, SPG
ADLER, BD
HANSELL, DM
MULLER, NL
机构
[1] VANCOUVER GEN HOSP,DEPT RADIOL,855 W 12TH AVE,VANCOUVER V5Z 1M9,BC,CANADA
[2] UNIV BRITISH COLUMBIA,DEPT RADIOL,VANCOUVER V6T 1W5,BC,CANADA
[3] ROYAL BROMPTON NATL HEART & LUNG HOSP,DEPT RADIOL,LONDON,ENGLAND
关键词
D O I
10.1016/S0009-9260(05)81129-8
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
In order to characterize the appearances of bronchiolitis obliterans on high-resolution CT (HRCT) and to relate the extent of HRCT abnormalities to pulmonary function tests, the HRCT scans of 18 patients with bronchiolitis obliterans were examined by two independent observers. The underlying causes for the development of bronchiolitis obliterans were penicillamine therapy (n = 5), previous infection (n = 4), graft-vs-host disease (n = 3), and miscellaneous causes (n = 6). Abnormal HRCT findings were present in all cases. The commonest HRCT abnormalities consisted of patchy areas of decreased parenchymal attenuation (n = 15), subsegmental (n = 12) and segmental (n = 6) bronchial dilatation and centrilobular branching structures (n = 5). There was no significant correlation between the extent of abnormalities and the static lung volumes or the impairment in gas transfer (all P values > 0.05). The only significant correlation was between the number of segments with subsegmental bronchial dilatation and the forced expiratory volume in one second (Wilcoxon r = 0.61, P < 0.01). We conclude that the great majority of patients with bronchiolitis obliterans have HRCT abnormalities. However, there is poor correlation between the extent of abnormalities on HRCT and functional impairment.
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页码:236 / 240
页数:5
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