USEFUL SYNTHESIS OF 3-(2-PYRIDYL)-COUMARINS AND 8-(2-PYRIDYL)COUMARINS

被引：0
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作者：
BRAHMBHATT, DI
HIRANI, BR
机构：
来源：
INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY | 1994年 / 33卷 / 11期
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中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
3-(omega-Bromoacetyl)coumarin (1) and 4-methyl-7-methoxy-8-(omega-bromoacetyl)coumarin (5) on reaction with pyridine in refluxing toluene provide the pyridinium salts 2 and 6 respectively. Condensation of salts 2 and 6 with chalcones (3a-f) in acetic acid in the presence of ammonium acetate give 3-(2-pyridyl)- and 8-(2-pyridyl)coumarins (4a-f and 7 a-f) in high yields.
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页码：1072 / 1074
页数：3
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