SYNCHRONOUS ENDOMETRIAL AND OVARIAN ADENOCARCINOMAS

Rare instances of endometrial & ovarian cancers presenting at the same time (synchronous) have been reported in literature with their incidence rate ranging from 2-8.5%. They may or may not share the same histologic features. When they share identical histology, it is difficult to categorize them as two independent primaries or as one primary with metastasis in the other. Despite the difficulty, prognostication depends on this differentiation since two independent primary tumors with identical histology carry a better prognosis than the other category. Molecular genetics may be the sole answer when such a difficulty is encountered. We present one such quizzical case of synchronous endometrial & ovarian adenocarcinomas with similar histology occurring in a 51 year old female.