NUCLEOTIDE-SEQUENCE AND CHARACTERIZATION OF ERYTHROMYCIN RESISTANCE DETERMINANT THAT ENCODES MACROLIDE 2'-PHOSPHOTRANSFERASE-I IN ESCHERICHIA-COLI

被引：81
|
作者：
NOGUCHI, N
EMURA, A
MATSUYAMA, H
OHARA, K
SASATSU, M
KONO, M
机构：
[1] Department of Microbiology, School of Pharmacy, Tokyo Univ. of Pharmacy/Life Science, Hachioji, Tokyo 192-03
来源：
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 1995年 / 39卷 / 10期
关键词：
D O I：
10.1128/AAC.39.10.2359
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
The DNA fragment (3.3 kb) containing the erythromycin resistance determinant was cloned from Escherichia coli Tf481A and sequenced. Deletion and complementation analyses indicated that the expression of high-level resistance to erythromycin requires two genes, mphA and mrx, which encode macrolide 2'-phosphotransferase I and an unidentified hydrophobic protein, respectively.
引用
收藏
页码：2359 / 2363
页数：5
相关论文
共 50 条
  • [31] COMPLETE NUCLEOTIDE-SEQUENCE OF THE ESCHERICHIA-COLI RECB GENE
    FINCH, PW
    STOREY, A
    CHAPMAN, KE
    BROWN, K
    HICKSON, ID
    EMMERSON, PT
    NUCLEIC ACIDS RESEARCH, 1986, 14 (21) : 8573 - 8582
  • [32] THE COMPLETE NUCLEOTIDE-SEQUENCE OF THE TDC REGION OF ESCHERICHIA-COLI
    SCHWEIZER, HP
    DATTA, P
    NUCLEIC ACIDS RESEARCH, 1989, 17 (10) : 3994 - 3994
  • [33] NUCLEOTIDE-SEQUENCE OF THE MANNITOL (MTL) OPERON IN ESCHERICHIA-COLI
    DAVIS, T
    YAMADA, M
    ELGORT, M
    SAIER, MH
    MOLECULAR MICROBIOLOGY, 1988, 2 (03) : 405 - 412
  • [34] THE NUCLEOTIDE-SEQUENCE OF THE SPC OPERON FROM ESCHERICHIA-COLI
    CERRETTI, DP
    FEDERATION PROCEEDINGS, 1982, 41 (04) : 1035 - 1035
  • [35] COMPLETE NUCLEOTIDE-SEQUENCE OF THE ESCHERICHIA-COLI GLYA GENE
    PLAMANN, MD
    STAUFFER, LT
    URBANOWSKI, ML
    STAUFFER, GV
    NUCLEIC ACIDS RESEARCH, 1983, 11 (07) : 2065 - 2075
  • [36] NUCLEOTIDE-SEQUENCE OF THE GINA CONTROL REGION OF ESCHERICHIA-COLI
    COVARRUBIAS, AA
    BASTARRACHEA, F
    MOLECULAR & GENERAL GENETICS, 1983, 190 (01): : 171 - 175
  • [37] COMPLETE NUCLEOTIDE-SEQUENCE OF THE ESCHERICHIA-COLI ARGA GENE
    BROWN, K
    FINCH, PW
    HICKSON, ID
    EMMERSON, PT
    NUCLEIC ACIDS RESEARCH, 1987, 15 (24) : 10586 - 10586
  • [38] NUCLEOTIDE-SEQUENCE OF THE ESCHERICHIA-COLI REPLICATION GENE DNAZX
    YIN, KC
    BLINKOWA, A
    WALKER, JR
    NUCLEIC ACIDS RESEARCH, 1986, 14 (16) : 6541 - 6549
  • [39] THE COMPLETE NUCLEOTIDE-SEQUENCE OF THE TRYPTOPHAN OPERON OF ESCHERICHIA-COLI
    YANOFSKY, C
    PLATT, T
    CRAWFORD, IP
    NICHOLS, BP
    CHRISTIE, GE
    HOROWITZ, H
    VANCLEEMPUT, M
    WU, AM
    NUCLEIC ACIDS RESEARCH, 1981, 9 (24) : 6647 - 6668
  • [40] COMPLETE NUCLEOTIDE-SEQUENCE OF THE ESCHERICHIA-COLI GDHA GENE
    MCPHERSON, MJ
    WOOTTON, JC
    NUCLEIC ACIDS RESEARCH, 1983, 11 (15) : 5257 - 5266
12345