STATUS OF, AND DEVELOPMENTS IN, MASS-SPECTROMETRY OF PEPTIDES AND PROTEINS

被引:13
|
作者
ROEPSTORFF, P [1 ]
RICHTER, WJ [1 ]
机构
[1] CIBA GEIGY AG, DEPT PHYS, CH-4002 BASEL, SWITZERLAND
关键词
D O I
10.1016/0168-1176(92)85085-E
中图分类号
O64 [物理化学(理论化学)、化学物理学]; O56 [分子物理学、原子物理学];
学科分类号
070203 ; 070304 ; 081704 ; 1406 ;
摘要
Four mass spectrometric methods - plasma desorption, fast atom bombardment, electrospray and laser desorption - are presently used for peptide and protein analysis. Their strengths and limitations are evaluated relative to the class of compound, the type of analytical information required and the performance parameters. Finally, the prospects for the future role of mass spectrometry in protein chemistry are predicted.
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页码:789 / 809
页数:21
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