RESOLUTION OF RACEMIC CARBOXYLIC-ACIDS VIA THE LIPASE-CATALYZED IRREVERSIBLE TRANSESTERIFICATION USING VINYL ESTERS - EFFECTS OF ALCOHOLS AS NUCLEOPHILES AND ORGANIC-SOLVENTS ON ENANTIOSELECTIVITY

被引：14

作者：

MIYAZAWA, T ^{[1
]}

KURITA, S ^{[1
]}

UEJI, S ^{[1
]}

YAMADA, T ^{[1
]}

KUWATA, S ^{[1
]}

机构：

[1] KOBE UNIV,COLL GEN EDUC,DEPT CHEM,NADA KU,KOBE 657,JAPAN

来源：

BIOTECHNOLOGY LETTERS | 1992年 / 14卷 / 10期

关键词：

D O I：

10.1007/BF01020634

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

The lipase-catalyzed irreversible transesterification procedure using vinyl esters has been applied to the resolution of racemic 2-phenoxypropanoic acids. The enantioselectivity was found to be affected profoundly by both the alcohol as a nucleophile and the organic solvent used.

引用

页码：941 / 946

页数：6