RESOLUTION OF RACEMIC CARBOXYLIC-ACIDS VIA THE LIPASE-CATALYZED IRREVERSIBLE TRANSESTERIFICATION USING VINYL ESTERS - EFFECTS OF ALCOHOLS AS NUCLEOPHILES AND ORGANIC-SOLVENTS ON ENANTIOSELECTIVITY

被引：14
|
作者：
MIYAZAWA, T [1 ]
KURITA, S [1 ]
UEJI, S [1 ]
YAMADA, T [1 ]
KUWATA, S [1 ]
机构：
[1] KOBE UNIV,COLL GEN EDUC,DEPT CHEM,NADA KU,KOBE 657,JAPAN
来源：
BIOTECHNOLOGY LETTERS | 1992年 / 14卷 / 10期
关键词：
D O I：
10.1007/BF01020634
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
The lipase-catalyzed irreversible transesterification procedure using vinyl esters has been applied to the resolution of racemic 2-phenoxypropanoic acids. The enantioselectivity was found to be affected profoundly by both the alcohol as a nucleophile and the organic solvent used.
引用
收藏
页码：941 / 946
页数：6
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