DETECTION OF INTERCALATION BEHAVIORS OF DYES IN DNAS USING A QUARTZ-CRYSTAL MICROBALANCE

被引:13
|
作者
OKAHATA, Y
MATSUZAKI, Y
IJIRO, K
机构
[1] Department of Biomolecular Engineering, Tokyo Institute of Technology, Meguno-ku, Tokyo, 152, Ookayama
关键词
D O I
10.1016/0925-4005(93)85406-Z
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
A water-insoluble, self-standing cast film of a DNA-lipid complex is prepared by mixing aqueous solutions of both anionic DNAs and cationic amphiphiles at a charge ratio of 1:1. Intercalation behaviours of dye molecules into a cast film of a DNA-lipid complex deposited on a quartz-crystal microbalance (QCM) are followed quantitatively by observing frequency changes of the QCM in an aqueous solution.
引用
收藏
页码:380 / 383
页数:4
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