CONTRIBUTION OF PREPARATIVE CHROMATOGRAPHIC RESOLUTION TO THE INVESTIGATION OF CHIRAL PHENOMENA

In the context of the investigation of the consequences of chirality on physical and biological phenomena, the demand for new general methods for preparing optically pure compounds in growing rapidly. In this respect, preparative chromatographic resolution on chiral stationary phases has been recognized as powerful tool and its usefulness is demonstrated in this review with applications covering different fields and different kinds of molecular chirality. The applications are arranged in tables according to their use such as for drugs, pesticides, chiral agents and auxiliaries, or to their stereogenic unit.