CRISSCROSS REGULATION OF CELL-TYPE-SPECIFIC GENE-EXPRESSION DURING DEVELOPMENT IN BACILLUS-SUBTILIS

被引:337
|
作者
LOSICK, R [1 ]
STRAGIER, P [1 ]
机构
[1] INST BIOL PHYSICOCHEM,F-75005 PARIS,FRANCE
关键词
D O I
10.1038/355601a0
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Sporulation in Bacillus subtilis is a model for how cells of one type generate other differentiated cell types. During sporulation two cellular compartments arise that differ from each other and from the progenitor cell. Differential gene expression between the two is governed by the successive appearance of four transcription factors whose activities are coordinated in crisscross fashion between the two cells.
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页码:601 / 604
页数:4
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