CLINICAL STUDY OF PREGNANCY WITH HYPOTHYROIDISM AND ITS OUTCOME IN TERTIARY CARE HOSPITAL

AIM: To study the incidence of hypothyroidism in pregnancy and its effect on maternal and fetal outcome. METHOD: Fifty pregnant women who delivered in VIMS Medical College Hospital, Bellary, during the study period of November 2013 till October 2014 were evaluated for the study. TSH screening was done in first antenatal visit. Those patients with TSH levels >2.5miu/L in first trimester and >3miu/l in second and third trimester were supplemented with thyroid hormone. The proportion of hypothyroidism in pregnancy during the study period was calculated. Their obstetric outcome in terms of abortion, anemia, preterm delivery, pre-eclampsia and perinatal outcome in terms of low birth weight. RESULTS: The incidence of hypothyroidism in pregnancy was 6.3%. Maternal complications included anemia 18%, pre-eclampsia 16%, GDM-4%, PPH 6%, preterm delivery 4% and abruptio placentae 2%. CONCLUSION: The incidence of hypothyroidism in pregnancy is found to be very high. By timely screening and supplementing thyroxin in patients with hypothyroidism maternal and fetal complication can be prevented, so routine screening of thyroid dysfunction is recommended in pregnancy.