LOCALIZATION OF THE RETINOID X-RECEPTOR ALPHA-GENE (RXRA) TO CHROMOSOME-9Q34

被引：9

作者：

JONES, KA

FITZGIBBON, J

WOODWARD, KJ

GOUDIE, D

FERGUSONSMITH, MA

POVEY, S

WOLFE, J

SOLOMON, E

机构：

[1] UNIV LONDON UNIV COLL,GALTON LAB,LONDON WC1E 6BT,ENGLAND

[2] UNIV CAMBRIDGE,DEPT PATHOL,CAMBRIDGE,ENGLAND

[3] UNIV LONDON UNIV COLL,MRC,HUMAN BIOCHEM GENET UNIT,LONDON WC1E 6BT,ENGLAND

来源：

ANNALS OF HUMAN GENETICS | 1993年 / 57卷

关键词：

D O I：

10.1111/j.1469-1809.1993.tb01595.x

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

The retinoid X receptor alpha is one of a number of retinoic acid receptors which are members of the steroid/thyroid hormone superfamily. Localization of RXRA was achieved using the polymerase chain reaction on a panel of somatic cell hybrids. A cosmid clone was isolated using the RXRA PCR product, and this was used to further localize the gene by fluorescence in situ hybridization to chromosome 9q34 distal to the dopamine beta hydroxylase gene (DBH). This mapping position was confirmed by PCR on a panel of translocation hybrids.

引用

页码：195 / 201

页数：7

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